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Apigenin

(HB0117)
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Product overview

Name Apigenin
Purity >98%
Description PKC inhibitor
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (4) Frequently bought together
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Biological Data

Biological description Protein kinase C (PKC) inhibitor that competes with ATP (IC50 = 30 µM for protein kinase CK2). Promotes cell cycle arrest and apoptosis. Displays antioxidant, anticarcinogenic and anti-inflammatory properties. A naturally occurring plant flavone.

Solubility & Handling

Solubility overview Soluble in DMSO (27mg/ml) or KOH (50mg/ml, 1M KOH)
Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name 4′,5,7-Trihydroxyflavone
Molecular Weight 270.3
Chemical structure Apigenin [520-36-5] Chemical Structure
Molecular Formula C15H10O5
CAS Number 520-36-5
PubChem identifier 5280443
SMILES C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O
InChiKey KZNIFHPLKGYRTM-UHFFFAOYSA-N

References for Apigenin

References are publications that support the biological activity of the product

  • Apigenin and cancer chemoprevention: progress, potential and promise (review).

    Patel D et al (2007) Int J Oncol 30(1) : 233-45.
    Read more (PubMedID: 17143534)

  • Molecular targets for apigenin-induced cell cycle arrest and apoptosis in prostate cancer cell xenograft.

    Shukla S et al (2006) Mol Cancer Ther 5(4) : 843-52.
    Read more (PubMedID: 16648554)

  • Inhibition of protein kinase CK2 prevents the progression of glomerulonephritis.

    Yamada M et al (2005) Proc Natl Acad Sci U S A 102(21) : 7736-41.
    Read more (PubMedID: 15897466)

  • Suppression of protein kinase C and nuclear oncogene expression as possible molecular mechanisms of cancer chemoprevention by apigenin and curcumin.

    Lin JK et al (1997) J Cell Biochem Suppl 28-29 : 39-48.
    Read more (PubMedID: 9589348)

4 Item(s)

Grouped product items
Order: HB0117
Pack PriceQty
100mg
$439
PKC inhibitor
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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