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Apigenin

(HB0117)
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Product overview

Name Apigenin
Purity >98%
Description PKC inhibitor
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (4) Frequently bought together
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Biological Data

Biological description Protein kinase C (PKC) inhibitor that competes with ATP (IC50 = 30 µM for protein kinase CK2). Promotes cell cycle arrest and apoptosis. Displays antioxidant, anticarcinogenic and anti-inflammatory properties. A naturally occurring plant flavone.

Solubility & Handling

Storage instructions +4°C
Solubility overview Soluble in DMSO (27mg/ml) or KOH (50mg/ml, 1M KOH)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name 4′,5,7-Trihydroxyflavone
Molecular Weight 270.3
Chemical structure Apigenin [520-36-5] Chemical Structure
Molecular Formula C15H10O5
CAS Number 520-36-5
PubChem identifier 5280443
SMILES C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O
InChiKey KZNIFHPLKGYRTM-UHFFFAOYSA-N

References for Apigenin

References are publications that support the biological activity of the product

  • Apigenin and cancer chemoprevention: progress, potential and promise (review).

    Patel D et al (2007) Int J Oncol 30(1) : 233-45.
    Read more (PubMedID: 17143534)

  • Molecular targets for apigenin-induced cell cycle arrest and apoptosis in prostate cancer cell xenograft.

    Shukla S et al (2006) Mol Cancer Ther 5(4) : 843-52.
    Read more (PubMedID: 16648554)

  • Inhibition of protein kinase CK2 prevents the progression of glomerulonephritis.

    Yamada M et al (2005) Proc Natl Acad Sci U S A 102(21) : 7736-41.
    Read more (PubMedID: 15897466)

  • Suppression of protein kinase C and nuclear oncogene expression as possible molecular mechanisms of cancer chemoprevention by apigenin and curcumin.

    Lin JK et al (1997) J Cell Biochem Suppl 28-29 : 39-48.
    Read more (PubMedID: 9589348)

4 Item(s)

Grouped product items
Order: HB0117
Pack PriceQty
100mg
$426
PKC inhibitor
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

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