Cytokine Storm / Immune response signaling
Cytokine storm describes an excessive immune response to external stimuli with the release of a large amount of pro-inflammatory cytokines. Cytokine storms occur in a range of infections and non-infectious diseases including COVID-19. The cytokine storm involves a variety of immune-related molecules such as interferon, interleukins, chemokines, CSFs and TNF-α. Increase in proinflammatory cytokines results in an influx of immune cells such as macrophages, T-Cells and neutrophils. The immune response to SARS-CoV2 infection also involves various signaling pathways. Researchers can save up to 50% on small molecules that affect cytokine storm and the immune response, as they are up to half the price of other suppliers.
View products: Angiotensin related | Cytokines, chemokines & NF-κB/I-κB | Inflammasomes | JAK/STAT | MAPK Signaling | PI3K/Akt/mTOR | Protease-Activated Receptors | TLR signaling
CGP 37157 (HB1132)
Description:Potent, selective mitochondria Na+ / Ca2+ exchange inhibitor
Purity:>99%
Cyclosporin A (HB0220)
Description:Potent calcineurin inhibitor. Inhibits MPTP opening.
Purity:>99%
Disulfiram (HB1119)
Description:Reversibly stimulates SERCA Ca2+-ATPase. V-ATPase inhibitor.
Purity:>97%
KB-R7943 mesylate (HB1133)
Description:Selective, reverse mode Na+ / Ca2+ exchange inhibitor
Purity:>99%
KN-62 (HB0359)
Description:Selective CaM kinase II inhibitor. P2X7 receptor antagonist.
Purity:>98%
MG132 (HB4135)
Description:Potent, cell-permeable proteasome inhibitor. Calpain inhibitor. Apoptosis inducer.
Purity:>95%
Paxilline (HB1056)
Description:Potent, reversible, selective KCa channel inhibitor. Also SERCA inhibitor.
Purity:>98%