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Artemisinin

(HB1115)
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Product overview

Name Artemisinin
Alternative names Qinghaosu
Purity >99%
Description Plasmodium falciparum SERCA orthologue inhibitor
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3)
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Biological Data

Biological description Plasmodium falciparum SERCA orthologue (PfATP6) inhibitor (Ki = 150 nM). Thought to generate cytotoxic C-radicals. Shows anti-malarial, anti-proliferative and anti-neoplastic actions.

Solubility & Handling

Solubility overview Soluble in DMSO (100mM) or ethanol (75mM)
Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >99%
Chemical name (3R,5aS,6R,8aS,9R,12S,12aR)-Octahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1, 2-benzodioxepin-10(3H)-one
Molecular Weight 282.33
Chemical structure Artemisinin [63968-64-9] Chemical Structure
Molecular Formula C15H22O5
CAS Number 63968-64-9
PubChem identifier 68827
SMILES O=C1O[C@]([H])(O[C@@](OO4)(C)CC3)[C@]24[C@](CC[C@@H](C)[C@]32[H])([H])[C@H]1C
InChiKey BLUAFEHZUWYNDE-NNWCWBAJSA-N

References for Artemisinin

References are publications that support the biological activity of the product

  • Artemisinin inhibits neuroblastoma proliferation through activation of AHP-activated protein kinase (AMPK) signaling.

    Tan WQ et al (2014) Pharmazie 69(6) : 468-72.
    Read more (PubMedID: 24974584)

  • Considerations on the mechanism of action of artemisinin antimalarials: part 1--the 'carbon radical' and 'heme' hypotheses.

    Haynes RK et al (2013) Infect Disord Drug Targets 13(4) : 217-77.
    Read more (PubMedID: 24304352)

  • Artemisinins target the SERCA of Plasmodium falciparum.

    Eckstein-Ludwig U et al (2003) Nature 424(6951) : 957-61.
    Read more (PubMedID: 12931192)

3 Item(s)

Grouped product items
Order: HB1115
Pack PriceQty
500mg
$486
1g
$729
Plasmodium falciparum SERCA orthologue inhibitor
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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