Product overview

Name Artemisinin
Alternative names Qinghaosu
Purity >99%
Description Plasmodium falciparum SERCA orthologue inhibitor
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Biological Data

Biological description Plasmodium falciparum SERCA orthologue (PfATP6) inhibitor (Ki = 150 nM). Thought to generate cytotoxic C-radicals. Shows anti-malarial, anti-proliferative and anti-neoplastic actions.

Solubility & Handling

Storage instructions +4°C
Solubility overview Soluble in DMSO (100mM) or ethanol (75mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.



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Chemical Data

Purity >99%
Chemical name (3R,5aS,6R,8aS,9R,12S,12aR)-Octahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1, 2-benzodioxepin-10(3H)-one
Molecular Weight 282.33
Chemical structure Artemisinin  [63968-64-9] Chemical Structure
Molecular Formula C15H22O5
CAS Number 63968-64-9
PubChem identifier 68827
SMILES O=C1O[C@]([H])(O[C@@](OO4)(C)CC3)[C@]24[C@](CC[C@@H](C)[C@]32[H])([H])[C@H]1C

References for Artemisinin

References are publications that support the biological activity of the product
  • Artemisinin inhibits neuroblastoma proliferation through activation of AHP-activated protein kinase (AMPK) signaling.

    Tan WQ et al (2014) Pharmazie 69(6) : 468-72.
  • Considerations on the mechanism of action of artemisinin antimalarials: part 1--the 'carbon radical' and 'heme' hypotheses.

    Haynes RK et al (2013) Infect Disord Drug Targets 13(4) : 217-77.
  • Artemisinins target the SERCA of Plasmodium falciparum.

    Eckstein-Ludwig U et al (2003) Nature 424(6951) : 957-61.

3 Item(s)