Anti-Amyloid Beta Antibody ValidAbTM

(HB6580)
Technical documents: SDS Datasheet

Product overview

Name Anti-Amyloid Beta Antibody ValidAbTM
Host Mouse
Clonality Monoclonal
Target Amyloid Beta
Description

Antibody to Amyloid Beta (Aβ) - neurotoxic peptide species that aggregates into plaques. Part of the ValidAb™ range of highly validated, data-rich antibodies.

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Validation data

Figure 1. TEST TEST TEST TEST

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Figure 2. TEST TEST TEST TEST

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Figure 3. TEST TEST TEST TEST

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Product information

Immunogen

Carrier protein conjugated with residues 1-17 of human Aβ1-42

Clone number BAM7cc
Isotype IgG1
Purification

Protein A affinity chromatography

Concentration 1mg/ml
Formulation Lyophilized. When reconstituted contains PBS with 1% recombinant albumin and 0.09% sodium azide
Predicted species reactivity Human
Tested species reactivity Human

Tested applications

Applications ELISA, WB
Application notes

This antibody was raised to a N-terminal sequence of Amyloid Beta therefore will not recognise Amyloid β 25-35 peptide species.

Target information

UniProt ID P05067 (Amyloid Precursor Protein)
Structure image  Chemical Structure
NCBI full gene name APP
Entrez gene ID

351

Amino acids

Dependent upon Aβ species however the most common species are:

  • Amyloid Beta 1-40
  • Amyloid Beta 1-42
  • Amyloid Beta 25-35 (not recognized by this antibody)

Storage & Handling

Storage instructions

-20°C then use reconstitution advice

Reconstitution advice

Upon receipt store at either -20°C or -80°C.

 

For 100μg packs either:

  • Reconstitute with 100μl dH2O and store at 4°C
  • Reconstitute with 50μl dH2O and 50μl glycerol then store at -20°C
  • Reconstitute with 100μl dH2O, aliquot then snap freeze and store at -80°C

For 25μg packs either:

  • Reconstitute with 25μl dH2O and store at 4°C
  • Reconstitute with 12.5μl dH2O and 12.5μl glycerol then store at -20°C
  • Reconstitute with 25μl dH2O, aliquot then snap freeze and store at -80°C

 

For more information read our guide on the best care for your product. Take care when opening as the precipitate is extremely light and can easily be lost if disturbed. When reconstituting make sure that the antibody is thoroughly dissolved by pipetting up and down before giving the antibody a brief spin at 10,000g to make sure that all material is recovered and at the bottom of the tube.

Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

FAQs

Any other questions?

For any other questions about our antibody products please see our technical FAQs for antibodies

References for Anti-Amyloid Beta Antibody ValidAbTM

References are publications that support the biological activity of the product
  • Amyloid beta: structure, biology and structure-based therapeutic development

    Chen GF, Xu TH, Yan Y, Zhou YR, Jiang Y, Melcher K, Xu HE. (2017) Acta Pharmacol Sin. : 1205-1235
  • Amyloid β-peptide (1-42)-induced oxidative stress in Alzheimer disease: importance in disease pathogenesis and progression

    Butterfield DA, Swomley AM, Sultana R. (2013) Antioxid Redox Signal :
  • 3D structure of Alzheimer's amyloid-beta(1-42) fibrils

    Lührs T, Ritter C, Adrian M, Riek-Loher D, Bohrmann B, Döbeli H, Schubert D, Riek R. (2005) Proc Natl Acad Sci USA :