Antagonists & inhibitors
An antagonist is a drug or chemical that reduces the effect of an agonist. Competitive antagonists bind to the same site on a receptor as the agonist but do not activate it - thereby blocking the action of the agonist. Non-competitive antagonists block the action of the agonist by binding to a different site on the receptor (an allosteric or non-agonist site). A reversible antagonist binds non-covalently and can be washed out. An irreversible antagonist binds covalently and cannot be displaced by either competing ligands or washing. Inhibitors are drugs that can bind to a protein, such as an enzyme and decrease its activity. Researchers can save up to 50% on competitive antagonists, non-competitive antagonists, reversible and irreversible antagonists, and inhibitors from Hello Bio - they are up to half the price of other suppliers.
(3S,6R)-Lateritin (HB3694)
Description:Acyl-CoA cholesterol acyltransferase (ACAT) inhibitor
Purity:>97%
LDN193189 hydrochloride (LDN) (HB5624)
Description:Potent, selective ALK2/ALK3 inhibitor which also promotes neural induction of hPSCs. May be used as a component for brain organoid production.
Purity:>98%
Leupeptin hemisulfate (HB3958)
Description:Reversible trypsin-like and cysteine proteases inhibitor
Purity:>97%
Linagliptin (HB4637)
Description:Highly potent, selective, competitive dipeptidyl-peptidase 4 inhibitor
Purity:>98%