The store will not work correctly in the case when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
Images Latrunculin A product vial image | Hello Bio
Latrunculin A product vial image | Hello Bio Biological Data Biological description Actin polymerization inhibitor that binds to monomeric G actin (Kd = 0.2 µM). Also inhibits adenine nucleotide exchange on actin. Plays a role in depolymerization of tumor cell cytoskeleton and shows possible anti-inflammatory properties.
Solubility & Handling Storage instructions -20°C
Solubility overview Soluble in DMSO (10mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Chemical Data Chemical name 4-[(1R ,4Z ,8E ,10Z ,12S ,15R , 17R )-17-Hydroxy-5,12-dimethyl-3-oxo -2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17 -yl)-2-thiazolidinone
Chemical structure
Molecular Formula C22 H31 NO5 S
PubChem identifier 445420
SMILES C[C@H]/1CC[C@@H]2C[C@H](C[C@@](O2)([C@@H]3CSC(=O)N3)O)OC(=O)/C=C(CC/C=C/C=C1)/C
InChi InChI=1S/C22H31NO5S/c1-15-7-5-3-4-6-8-16(2)11-20(24)27-18-12-17(10-9-15)28-22(26,13-18)19-14-29-21(25)23-19/h3-5,7,11,15,17-19,26H,6,8-10,12-14H2,1-2H3,(H,23,25)/b4-3+,7-5-,16-11-/t15-,17-,18-,19+,22-/m1/s1
InChiKey DDVBPZROPPMBLW-IZGXTMSKSA-N
References for Latrunculin A References are publications that support the biological activity of the product
Characterization of the activities of actin-affecting drugs on tumor cell migration. Hayot C et al (2006) Toxicol Appl Pharmacol 211(1) : 30-40. Actin-latrunculin A structure and function. Differential modulation of actin-binding protein function by latrunculin A. Yarmola EG et al (2000) J Biol Chem 275(36) : 28120-7. Inhibition of actin polymerization by latrunculin A. Coué M et al (1987) FEBS Lett 213(2) : 316-8.
Actin polymerization inhibitor
![Latrunculin A [76343-93-6] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb0375.png "Latrunculin A [76343-93-6]")
Understanding purity and quality - a guide for life scientists