Product overview

Name Linagliptin
Purity >98%
Description Highly potent, selective, competitive dipeptidyl-peptidase 4 inhibitor
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Biological Data

Biological description Antidiabetic agent. Highly potent and selective competitive inhibitor of dipeptidyl-peptidase 4 (DPP4; DPP IV; CD26), an enzyme that degrades, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). Prevents the inactivation of endogenous GLP-1 and GIP. Shown to restore beta cell function and survival in human isolated islets through GLP-1 stabilization. Improves insulin sensitivity. Anti-inflammatory compound.

Solubility & Handling

Storage instructions +4°C
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Purity >98%
Chemical name 8-(3-(R)-Aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione
Molecular Weight 472.5
Chemical structure Linagliptin [668270-12-0] Chemical Structure
CAS Number 668270-12-0
InChiKey LTXREWYXXSTFRX-QGZVFWFLSA-N
Appearance White to off-white solid