Kv7 channel blocker. Increases ACh release in the brain and blocks M currents (IC50 = 2.4 µM). Induces increased neocortical Fos protein expression in aged rats. Also agonises TRPV1 (transient receptor potential vanilloid type 1) channel. Shows excitatory actions on nociceptors and shows cognition enhancing actions.
Solubility & Handling
Room temperature (desiccate)
Soluble in water (100mM) and in DMSO (100 mM)
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.