Agonists & activators
An agonist or activator, is a drug or chemical that binds to and activates a protein, such as receptor or enzyme. Full agonists have high efficacy, eliciting a full response whilst occupying a small proportion of receptors. Partial agonists have a lower efficacy and cannot produce a maximal response, even if occupying a high proportion of receptors. Inverse agonists can bind to the same receptor binding-site as an agonist, but elicit an opposite effect. Researchers can save up to 50% on activators, agonists, partial agonists and inverse agonists from Hello Bio - they are up to half the price of other suppliers.
- Description:
Antibody to tyrosine hydroxylase (TH) - the rate limiting enzyme in catecholamine synthesis and used as a marker for catecholaminergic (dopaminergic and noradrenergic) neurones in the CNS. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: ChickenClonality: PolyclonalReactivity Tested: Mouse, Rat - Description:
Antibody to tyrosine hydroxylase (TH) - the rate limiting enzyme in catecholamine synthesis and used as a marker for catecholaminergic (dopaminergic and noradrenergic) neurones in the CNS. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: Mouse, Rat - Description:
Antibody to VGAT - GABA transporter and GABAergic neuron marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: RabbitClonality: PolyclonalReactivity Tested: Mouse, Rat Anti-Vimentin antibody ValidAb™ (HB6497)
Description:Monoclonal antibody to Vimentin - class III intermediate filament expressed in mesenchymal cells used as a marker of epithelial-mesenchymal transition. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: Rat, Human, Mouse (no staining)Anti-BrdU antibody ValidAbTM (HB9919)
Description:Antibody to BrdU - thymidine analogue incorporated into DNA during replication therefore used as a marker of proliferating cells. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: NAAnti-Calbindin antibody ValidAb™ (HB6396)
Description:Antibody to Calbindin - calcium binding protein used as a marker for an inhibitory interneuron subtype. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: RatAnti-GluN1 antibody ValidAbTM (HB7535)
Description:Antibody to the GluN1 subunit of the NMDA receptor. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: Mouse, Rat- Description:
Goat Anti-Mouse IgG H&L Janelia Fluor® 549 secondary antibody. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: GoatClonality: Polyclonal - Description:
Goat Anti-Mouse IgG H&L Janelia Fluor® 525 secondary antibody. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: GoatClonality: Polyclonal - Description:
Antifade fluorescence hard-set mounting medium for use in IHC(IF) and ICC.