Nuclear Receptors

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Nuclear hormone receptors (nuclear receptors) are specialised transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can save up to 50% on nuclear hormone receptor agonists, antagonists and modulators from Hello Bio - they are up to half the price of other suppliers.

Items 301-310 of 319

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  1. Pack:
    50mg
    Price:
    $833
    Qty:
  2. Wnt-C59 (HB3155)

    Description:

    Highly potent PORCN inhibitor. Induces iPSC cardiomyocytes differentiation.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $259
    Qty:
    Pack:
    50mg
    Price:
    $1,013
    Qty:
  3. Wortmannin (HB2778)

    Description:

    Potent, selective, irreversible PI3-K inhibitor

    Purity:

    >99%

    Pack:
    1mg
    Price:
    Qty:
    Pack:
    5mg
    Price:
    $246
    Qty:
    Pack:
    10mg
    Price:
    $455
    Qty:
  4. Description:

    Serotonin/norepinephrine reuptake inhibitor (SNRI)

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $502
    Qty:
  5. XAV 939 (HB0660)

    Description:

    Potent tankyrase inhibitor. Wnt/β-catenin signaling inhibitor.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    Qty:
    Pack:
    10mg
    Price:
    $110
    Qty:
    Pack:
    25mg
    Price:
    $246
    Qty:
    Pack:
    50mg
    Price:
    $446
    Qty:
  6. 6  Reviews
    Top Reviews:
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    Description:

    Y-27632 is a selective ROCK inhibitor. Frequently used 3D growth matrix component and for production of organoids. Also used when inducing neurons from fibroblasts. Manufactured to a high degree of optical purity.

    Purity:

    >99%

    Pack:
    1mg
    Price:
    $44
    Qty:
    Pack:
    2mg
    Price:
    Qty:
    Pack:
    5mg
    Price:
    $119
    Qty:
    Pack:
    10mg
    Price:
    $168
    Qty:
    Pack:
    5x10mg
    Price:
    $754
    Qty:
    Pack:
    25mg
    Price:
    $325
    Qty:
    Pack:
    50mg
    Price:
    $564
    Qty:
    Pack:
    10mM solution (in 1mL DMSO)
    Price:
    $172
    Qty:
  7. YM-254890 (HB6283)

    Description:

    Potent Gq/11 signaling inhibitor. Reported as Gq- G-protein inhibitor and broad-spectrum inhibitor for Gq- and Gs-proteins.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $421
    Qty:
  8. Z-DEVD-FMK (HB1282)

    Description:

    Irreversible, selective caspase 3 inhibitor

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $299
    Qty:
    Pack:
    5mg
    Price:
    $1,211
    Qty:
  9. Z-DQMD-FMK (HB1283)

    Description:

    Cell permeable caspase 3 specific inhibitor

    Pack:
    1mg
    Price:
    $293
    Qty:
    Pack:
    5mg
    Price:
    $1,189
    Qty:
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