Mineralocorticoid

Novel DREADD agonist with high affinity and potency for hM3Dq and hM4Di. Active in vivo. Water soluble.

Prototypic, selective kainate receptor agonist. Potent excitant and neurotoxin.

Exercise induced metabolite that supresses food intake and obesity

Deuterated Lac-Phe (N-lactoyl-phenylalanine)

Potent and selective ACKR3 (CXCR7) agonist. Potentiates opioid peptide activity.

Novel, potent covalent A_2A antagonist. Binds irreversibly.

Novel, covalent Affinity-Based Probe (AfBP). Clickable antagonist for the A₂AR.

Novel, intracellular covalent chemokine CCR2 negative allosteric modulator (NAM). Binds irreversibly.

Novel, potent, selective A₃AR covalent antagonist

The first covalent hA₁AR partial agonist. Binds Irreversibly.