DREADD
Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
- Description:
Novel DREADD agonist with high affinity and potency for hM3Dq and hM4Di. Active in vivo. Water soluble.
Purity:>98%
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Kainic acid (HB0355)
Description:Prototypic, selective kainate receptor agonist. Potent excitant and neurotoxin.
Purity:>98%
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Kynurenic acid (HB0362)
Description:Endogenous ionotropic glutamate / nicotinic antagonist.
Purity:>98%
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Lac-Phe (N-lactoyl-phenylalanine) (HB8782)
Description:Exercise induced metabolite that supresses food intake and obesity
Purity:>99%
- Description:
Deuterated Lac-Phe (N-lactoyl-phenylalanine)
Purity:>97%
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