DREADD
Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
Naspm trihydrochloride (HB0441)
Description:Selective GluA2- lacking, Ca2+ permeable AMPA / kainate receptor antagonist
Purity:>95%
-
NBQX disodium salt (HB0443)
Description:Potent, selective, competitive AMPA receptor antagonist. Disodium salt.
Purity:>99%
-
-
-
-
-
-
SR 95531 hydrobromide (Gabazine) (HB0901)
Description:Selective, competitive GABAA receptor antagonist
Purity:>98%
-
(S)-(-)-Sulpiride (HB1836)
Description:Selective D2-like receptor antagonist. Active enantiomer.
Purity:>99%
