G protein coupled receptors
G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
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- Description:
Novel caged, fast-equilibrating glutamate receptor antagonist. Suitable for use as a synaptic probe.
Purity:>98%
Naspm trihydrochloride (HB0441)
Description:Selective GluA2- lacking, Ca2+ permeable AMPA / kainate receptor antagonist
Purity:>95%
NBQX disodium salt (HB0443)
Description:Potent, selective, competitive AMPA receptor antagonist. Disodium salt.
Purity:>99%
SR 95531 hydrobromide (Gabazine) (HB0901)
Description:Selective, competitive GABAA receptor antagonist
Purity:>98%
Talampanel (HB0600)
Description:Selective, non-competitive AMPA / kainate receptor antagonist
Purity:>98%
TCN 201 (HB0604)
Description:Potent, non-competitive GluN2A subunit selective NMDA receptor antagonist
Purity:>99%
Tropisetron hydrochloride (HB2827)
Description:Potent 5-HT3 receptor antagonist. Also α7 nAChR partial agonist. Activates α7Q79G-GlyR chimeric ion channels.
Purity:>99%