GluN2

Potent Ca²⁺ release inhibitor

Potent, selective KORD DREADD activator

Potent GABA_B receptor agonist

Reported to be a potent, selective Ca_v2.3 (R-type) channel blocker

TRPV6 antagonist

Selective, competitive GABA_A receptor antagonist

Selective, non-competitive AMPA / kainate receptor antagonist

TRPM2 antagonist. Cell permeable.

Abundant free amino acid found in the brain.

Potent, selective Na_v1.7 inhibitor