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G-protein receptor kinases (GRKs) help terminate GPCR signaling through receptor desensitization and downregulation and also modulate signaling via phosphorylation-independent functions. GRKs affect various physiological processes. Researchers can save up to 50% on GRK modulators from Hello Bio - they are around half the price of other suppliers.
A83-01 (HB3218)
Description:Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.
Purity:>98%
AY 9944 dihydrochloride (HB3543)
Description:Hedgehog signaling inhibitor. Δ,7-dehydrocholesterol reductase inhibitor.
Purity:>99%
Bisindolylmaleimide IV (HB0137)
Description:Selective, non-competitive PKC / PKA inhibitor
Purity:>98%