AMPK

Phosphoinositide 3-kinase (PI3K)/Akt pathway inhibitor

Selective TRPC6 channel activator and neurotransmitter re-uptake inhibitor

Non-selective endogenous glycine receptor agonist 

Potent, selective Bruton's tyrosine kinase (BTK) inhibitor.

Potent TRPM8 channel agonist

Potent muscarinic acetylcholine receptor superagonist. Also binds the hM3R-miniG_q DREADD receptor.

Piezo1 channel activator

Prototypic, selective kainate receptor agonist. Potent excitant and neurotoxin.

Potent, selective PKA inhibitor

Potent, selective mTOR inhibitor