Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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    Description:

    Potent, selective and metabolically stable hM3Dq and hM4Di muscarinic DREADD actuator.

    Purity:

    >98%

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    $58
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    $90
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    50mM (add 1ml water)
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  5. Description:

    Less toxic, degradation product of Anatoxin-A

    Purity:

    >95% (NMR)

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  7. 26  Reviews
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    Description:

    Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator. Brain penetrant. Water soluble.

    Purity:

    >98%

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    $33
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    $88
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    $361
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    $1,045
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  8. Description:

    Potent CK2 inhibitor

    Purity:

    >98%

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    50mg
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    $58
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  9. Endomorphin-1 (HB2410)

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    Potent, selective μ-opioid receptor agonist

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    5mg
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    $94
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