PI3K/Akt/mTOR

Protein synthesis inhibitor

Selective Hsp90 inhibitor. Breast cancer stem cell inhibitor.

Potent, selective JAK2 inhibitor

Protein synthesis inhibitor

Phosphoinositide 3-kinase (PI3K)/Akt pathway inhibitor

Pan kinase inhibitor. Potently inhibits MEK1, Cdk1, Cdk2, Cdk3 and Cdk5 and GSK-3β.

Potent, reversible p38α MAPK inhibitor

PKC inhibitor

Potent, selective mTOR inhibitor

Potent, non-selective tyrosine kinase inhibitor