References are publications that support the biological activity of the product
Growth hormone-stimulated insulin-like growth factor-1 expression in rainbow trout (Oncorhynchus mykiss) hepatocytes is mediated by ERK, PI3K-AKT, and JAK-STAT.
Reindl KM et al (2011) Am J Physiol Regul Integr Comp Physiol 301(1) : R236-43.
Jak2 inhibition deactivates Lyn kinase through the SET-PP2A-SHP1 pathway, causing apoptosis in drug-resistant cells from chronic myelogenous leukemia patients.
Samanta AK et al (2009) Oncogene 28(14) : 1669-81.
Identification of 1,2,3,4,5,6-hexabromocyclohexane as a small molecule inhibitor of jak2 tyrosine kinase autophosphorylation [correction of autophophorylation].
Sandberg EM et al (2005) J Med Chem 48(7) : 2526-33.
![1,2,3,4,5,6-Hexabromocyclohexane [1837-91-8] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb1428.png "1,2,3,4,5,6-Hexabromocyclohexane [1837-91-8]")
Understanding purity and quality - a guide for life scientists