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Inflammasome

Inflammasomes are an important part of the innate immune system which are activated upon cellular infection or stress to trigger maturation of proinflammatory cytokines. They regulate the activation of caspase-1 and induce an inflammatory response.
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  1. Anti-α-Synuclein antibody ValidAbTM (HB6378)

    Description:

    Antibody to Alpha-Synuclein - synaptic protein involved in neurodegeneration. Part of the ValidAbâ„¢ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat
    Figure 1. α-Synuclein staining in rat cerebellum localises to the molecular layer.
    Pack:
    25μg
    Price:
    $160
    Qty:
    Pack:
    100μg
    Price:
    $300
    Qty:
    Supporting Docs Add to Favorites

  2. Anti-Calbindin antibody ValidAbâ„¢ (HB6396)

    Description:

    Antibody to Calbindin - calcium binding protein used as a marker for an inhibitory interneuron subtype. Part of the ValidAbâ„¢ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Rat
    Figure 1. Calbindin and Calretinin expression in rat cerebellum
    Pack:
    25μg
    Price:
    $150
    Qty:
    Pack:
    100μg
    Price:
    $336
    Qty:
    Supporting Docs Add to Favorites

  3. Anti-GluN1 antibody ValidAbTM (HB7535)

    Description:

    Antibody to the GluN1 subunit of the NMDA receptor. Part of the ValidAbâ„¢ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat
    Anti-GluN1 antibody ValidAb<sup>TM</sup>
    Pack:
    3μg
    Price:
    $131
    Qty:
    Pack:
    15μg
    Price:
    $457
    Qty:
    Supporting Docs Add to Favorites

  4. Anti-βIII Tubulin antibody ValidAbTM (HB6639)

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    Description:

    Antibody to βIII Tubulin - cytoskeletal protein used as a neuronal marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat
    Figure 1. β3-tubulin expression in the Purkinje cells of the cerebellum labelled by HB6639.
    Pack:
    25μg
    Price:
    $136
    Qty:
    Pack:
    100μg
    Price:
    $311
    Qty:
    Supporting Docs Add to Favorites

  5. Anti-β-tubulin antibody ValidAb™ (HB6491)

    Description:

    Antibody to β-tubulin - cytoskeletal component widely used for imaging microtubules and as a loading control. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat, Human
    Figure 1. ß-Tubulin and Neurofilament L expression in cultured rat neurones
    Pack:
    25μg
    Price:
    $140
    Qty:
    Pack:
    100μg
    Price:
    $311
    Qty:
    Supporting Docs Add to Favorites

  6. Anti-c-Fos antibody ValidAbâ„¢ (HB8006)

    Description:

    Antibody to c-Fos - an immediate early gene used as a marker of neuronal activity. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse
    Figure 1. c-Fos expression in the dentate gyrus of TRAP2;Ai14 mice.
    Pack:
    25μg
    Price:
    $144
    Qty:
    Pack:
    100μg
    Price:
    $320
    Qty:
    Supporting Docs Add to Favorites

  7. Anti-GAPDH antibody ValidAbTM (HB9177)

    Description:

    Antibody to GAPDH - universal loading control for western blotting. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat, Human
    Figure 1. GAPDH expression in various tissue lysates and preparations.
    Pack:
    25μg
    Price:
    $140
    Qty:
    Pack:
    100μg
    Price:
    $320
    Qty:
    Supporting Docs Add to Favorites

  8. Anti-GFAP antibody ValidAbTM (HB8267)

    Description:

    Antibody to GFAP - cytoskeletal protein used as an astrocyte marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat
    Figure 1. GFAP expression in a rat cultured neurone preparation visualised using HB8267.
    Pack:
    25μg
    Price:
    $144
    Qty:
    Pack:
    100μg
    Price:
    $325
    Qty:
    Supporting Docs Add to Favorites

  9. Anti-GFP antibody ValidAbâ„¢ (HB6381)

    Description:

    Monoclonal antibody (IgM) to GFP - green coloured fluorescent protein widely used as a tag in molecular biology. Part of the ValidAb™ range of highly validated, data-rich antibodies. 

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Species Independent
    Figure 1. Specific HB6381 staining only in pEGFP-C2 transfected HEK293 cells.
    Pack:
    25μg
    Price:
    $140
    Qty:
    Pack:
    100μg
    Price:
    $311
    Qty:
    Supporting Docs Add to Favorites

  10. Anti-GST tag antibody ValidAbTM (HB9897)

    Description:

    Antibody to the GST tag - widely used as a protein tag in molecular biology. Part of the ValidAb™ range of highly validated, data-rich antibodies. 

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Species Independent
    Figure 1. Expression and purification of a GST-fusion protein monitored using HB9897.
    Pack:
    25μg
    Price:
    $145
    Qty:
    Pack:
    100μg
    Price:
    $324
    Qty:
    Supporting Docs Add to Favorites
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Category
Applications
  1. ELISA
  2. ICC
  3. IHC-P
  4. WB
  5. IHC(IF)
  6. Histoblot
Host
  1. Mouse
  2. Rabbit
  3. Goat
  4. Chicken
Target
  1. GluN1
  2. GFAP
  3. GAPDH
  4. NeuN
  5. Neurofilament L
  6. Beta III tubulin
  7. HSP60
  8. Neurofilament M
  9. GFP
  10. MAP2
  11. Tyrosine hydroxylase
  12. β-tubulin
  13. Myelin basic protein
  14. c-Fos
  15. Vimentin
  16. BrdU
  17. GST tag
  18. Parvalbumin
  19. Calbindin
  20. Ki-67
  21. α-Synuclein