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Inflammasome

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Inflammasomes are an important part of the innate immune system which are activated upon cellular infection or stress to trigger maturation of proinflammatory cytokines. They regulate the activation of caspase-1 and induce an inflammatory response.

Items 1-10 of 35

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  1. Antibody Diluent (HB8223)

    Description:

    Diluent used to dilute primary antibodies or for storage

    Pack:
    125mL
    Price:
    $127
    Qty:
    Pack:
    250mL
    Price:
    $216
    Qty:
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  2. Anti-βIII Tubulin antibody ValidAbTM (HB6639)

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    Description:

    Antibody to βIII Tubulin - cytoskeletal protein used as a neuronal marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat
    Figure 1. β3-tubulin expression in the Purkinje cells of the cerebellum labelled by HB6639.
    Pack:
    25μg
    Price:
    $136
    Qty:
    Pack:
    100μg
    Price:
    $311
    Qty:
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  3. Anti-c-Fos antibody ValidAbTM (HB8006)

    Description:

    Antibody to c-Fos - an immediate early gene used as a marker of neuronal activity. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse
    Figure 1. c-Fos expression in the dentate gyrus of TRAP2;Ai14 mice.
    Pack:
    25μg
    Price:
    $140
    Qty:
    Pack:
    100μg
    Price:
    $311
    Qty:
    Supporting Docs Add to Favorites

  4. Anti-Calretinin antibody ValidAbTM (HB6494)

    Description:

    Antibody to Calretinin - calcium binding protein used as a marker for an inhibitory interneuron subtype. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Rabbit
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    Figure 1. Calretinin and Parvalbumin expressing interneurons in the rat hippocampus
    Pack:
    25μL
    Price:
    $171
    Qty:
    Pack:
    100μL
    Price:
    $382
    Qty:
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  5. Anti-GAT1 Antibody ValidAbTM (HB7632)

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    Description:

    Antibody to GAT1 - GABA reuptake transporter and marker for GABAergic interneurones. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Rabbit
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    GAT1 expression in the rat cerebellum revealed with HB7632
    Pack:
    25μL
    Price:
    $179
    Qty:
    Pack:
    100μL
    Price:
    $536
    Qty:
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  6. Anti-GFAP antibody ValidAbTM (HB8267)

    Description:

    Antibody to GFAP - cytoskeletal protein used as an astrocyte marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat
    Figure 1. GFAP expression in a rat cultured neurone preparation visualised using HB8267.
    Pack:
    25μg
    Price:
    $140
    Qty:
    Pack:
    100μg
    Price:
    $316
    Qty:
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  7. Anti-GFAP antibody ValidAbTM (HB7592)

    Description:

    Antibody to GFAP - cytoskeletal protein used as an astrocyte marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Goat
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    Figure 1. Astrocytes in culture in a cultured rat neuron preparation.
    Pack:
    25μg
    Price:
    $197
    Qty:
    Pack:
    100μg
    Price:
    $442
    Qty:
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  8. Anti-GFAP antibody ValidAbTM (HB6406)

    Description:

    Antibody to GFAP - cytoskeletal protein used as an astrocyte marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Chicken
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    Figure 1. An astrocyte surrounded by neurons in a cultured rat neuron preparation.
    Pack:
    25μL
    Price:
    $164
    Qty:
    Pack:
    100μL
    Price:
    $366
    Qty:
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  9. Anti-GFAP antibody ValidAbTM (HB8001)

    Description:

    Antibody to GFAP - cytoskeletal protein used as an astrocyte marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Rabbit
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    Anti-GFAP antibody ValidAb<sup>TM</sup>
    Pack:
    25μL
    Price:
    $161
    Qty:
    Pack:
    100μL
    Price:
    $360
    Qty:
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  10. Anti-HSP60 antibody ValidAbTM (HB7863)

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    Description:

    Antibody to HSP60 - loading control and mitochondrial marker for immunohistochemistry and immunocytochemistry. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat, Human
    Figure 1. HSP60 staining with HB7863 reveals the dense mitochondria in cultured rat neurones.
    Pack:
    25μg
    Price:
    $155
    Qty:
    Pack:
    100μg
    Price:
    $352
    Qty:
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Biological action
  1. Buffer
Applications
  1. Antineoplastic Agent
  2. Cell Culture
  3. ELISA
  4. FACS and flow cytometry
  5. fluorescence imaging
  6. ICC
  7. IF
  8. IHC
  9. live cell imaging
  10. Plant Culture
  11. Selection Agent
  12. WB
  13. IHC(IF)
  14. Histoblot
Host
  1. Mouse
  2. Rabbit
  3. Goat
  4. Chicken
Target
  1. GluN1
  2. GFAP
  3. NeuN
  4. Neurofilament L
  5. Beta III tubulin
  6. HSP60
  7. Neurofilament M
  8. MAP2
  9. Tyrosine hydroxylase
  10. Myelin basic protein
  11. GAT1
  12. c-Fos
  13. Vimentin
  14. BrdU
  15. VGAT
  16. Parvalbumin
  17. Calretinin
  18. Calbindin
  19. Histone H3
  20. IBA1