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Inflammasome

Inflammasomes are an important part of the innate immune system which are activated upon cellular infection or stress to trigger maturation of proinflammatory cytokines. They regulate the activation of caspase-1 and induce an inflammatory response.
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  1. Anti-α-Synuclein antibody ValidAbTM (HB6378)

    Description:

    Antibody to Alpha-Synuclein - synaptic protein involved in neurodegeneration. Part of the ValidAbâ„¢ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat
    Figure 1. α-Synuclein staining in rat cerebellum localises to the molecular layer.
    Pack:
    25μg
    Price:
    $160
    Qty:
    Pack:
    100μg
    Price:
    $300
    Qty:
    Supporting Docs Add to Favorites

  2. Anti-Calbindin antibody ValidAbâ„¢ (HB6396)

    Description:

    Antibody to Calbindin - calcium binding protein used as a marker for an inhibitory interneuron subtype. Part of the ValidAbâ„¢ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Rat
    Figure 1. Calbindin and Calretinin expression in rat cerebellum
    Pack:
    25μg
    Price:
    $150
    Qty:
    Pack:
    100μg
    Price:
    $336
    Qty:
    Supporting Docs Add to Favorites

  3. Anti-GFAP antibody ValidAbâ„¢ (HB7592)

    Description:

    Antibody to GFAP - cytoskeletal protein used as an astrocyte marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Goat
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    Figure 1. Astrocytes in culture in a cultured rat neuron preparation.
    Pack:
    25μg
    Price:
    $197
    Qty:
    Pack:
    100μg
    Price:
    $442
    Qty:
    Supporting Docs Add to Favorites

  4. Anti-GluN1 antibody ValidAbTM (HB7535)

    Description:

    Antibody to the GluN1 subunit of the NMDA receptor. Part of the ValidAbâ„¢ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat
    Anti-GluN1 antibody ValidAb<sup>TM</sup>
    Pack:
    3μg
    Price:
    $131
    Qty:
    Pack:
    15μg
    Price:
    $457
    Qty:
    Supporting Docs Add to Favorites

  5. Anti-NeuN antibody ValidAbâ„¢ (HB9493)

    Description:

    Antibody to NeuN - marker for mature neurones expressed in the nucleus. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Goat
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    Figure 1. NeuN expressing neurons in the dentate gyrus visualised using HB9493.
    Pack:
    25μg
    Price:
    $144
    Qty:
    Pack:
    100μg
    Price:
    $320
    Qty:
    Supporting Docs Add to Favorites

  6. Antibody Diluent (HB8223)

    Description:

    Diluent used to dilute primary antibodies or for storage

    Pack:
    125mL
    Price:
    $131
    Qty:
    Pack:
    250mL
    Price:
    $222
    Qty:
    Supporting Docs Add to Favorites

  7. Anti-βIII Tubulin antibody ValidAbTM (HB6639)

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    Description:

    Antibody to βIII Tubulin - cytoskeletal protein used as a neuronal marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat
    Figure 1. β3-tubulin expression in the Purkinje cells of the cerebellum labelled by HB6639.
    Pack:
    25μg
    Price:
    $136
    Qty:
    Pack:
    100μg
    Price:
    $311
    Qty:
    Supporting Docs Add to Favorites

  8. Biotin Tyramide Signal Amplification Kit - AF488 (HB18560)

    Description:

    Immunofluorescent signal amplification kit using biotin tyramide and Streptavidin AF488.

    Figure 2: Parvalbumin positive neurons in the rat hippocampus, detected using biotin tyramide signal amplification
    Pack:
    100 reactions
    Price:
    $247
    Qty:
    Supporting Docs Add to Favorites

  9. Biotin Tyramide Signal Amplification Kit - Janelia Fluor® 525 (HB19791)

    Description:

    Immunofluorescent signal amplification kit using biotin tyramide and Streptavidin Janelia Fluor® 525.

    Figure 1: Tyramide Signal Amplification compared to detection using secondary biotin antibody and streptavidin
    Pack:
    100 reactions
    Price:
    $247
    Qty:
    Supporting Docs Add to Favorites

  10. Biotin Tyramide Signal Amplification Kit - Janelia Fluor® 549 (HB16587)

    Description:

    Immunofluorescent signal amplification kit using biotin tyramide and Streptavidin Janelia Fluor® 549.

    Figure 1: Tyramide signal amplification of parvalbumin positive interneurons in the rat hippocampus.
    Pack:
    100 reactions
    Price:
    $247
    Qty:
    Supporting Docs Add to Favorites
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Biological action
  1. Buffer
Applications
  1. Antineoplastic Agent
  2. Cell Culture
  3. ELISA
  4. FACS and flow cytometry
  5. fluorescence imaging
  6. ICC
  7. IF
  8. IHC
  9. IHC-P
  10. live cell imaging
  11. Plant Culture
  12. Selection Agent
  13. WB
  14. IHC(IF)
  15. Histoblot
  16. SDS-PAGE
Host
  1. Mouse
  2. Rabbit
  3. Goat
  4. Chicken
Clonality
  1. Monoclonal
  2. Polyclonal
Conjugate
  1. Janelia Fluor® 525
  2. Janelia Fluor® 549
  3. Janelia Fluor® 646
  4. AF488
  5. Biotin
Target
  1. GluN1
  2. GFAP
  3. NeuN
  4. Neurofilament L
  5. Beta III tubulin
  6. HSP60
  7. Neurofilament M
  8. MAP2
  9. Tyrosine hydroxylase
  10. Myelin basic protein
  11. GAT1
  12. c-Fos
  13. Vimentin
  14. BrdU
  15. Mouse IgG H&L
  16. Rabbit IgG H&L
  17. VGAT
  18. Parvalbumin
  19. Calretinin
  20. Calbindin
  21. Histone H3
  22. IBA1
  23. Chicken IgY H&L
  24. GluA1-4
  25. α-Synuclein