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Inflammasome

Inflammasomes are an important part of the innate immune system which are activated upon cellular infection or stress to trigger maturation of proinflammatory cytokines. They regulate the activation of caspase-1 and induce an inflammatory response.
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  1. Biotin Tyramide Signal Amplification Kit - Janelia Fluor® 646 (HB19874)

    Description:

    Immunofluorescent signal amplification kit using biotin tyramide and Streptavidin Janelia Fluor® 646.

    Figure 1: Tyramide Signal Amplification compared to detection using secondary biotin antibody and streptavidin
    Pack:
    100 reactions
    Price:
    $247
    Qty:
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  2. Anti-c-Fos antibody ValidAbâ„¢ (HB8006)

    Description:

    Antibody to c-Fos - an immediate early gene used as a marker of neuronal activity. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse
    Figure 1. c-Fos expression in the dentate gyrus of TRAP2;Ai14 mice.
    Pack:
    25μg
    Price:
    $144
    Qty:
    Pack:
    100μg
    Price:
    $320
    Qty:
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  3. Anti-Calretinin antibody ValidAbTM (HB6494)

    Description:

    Antibody to Calretinin - calcium binding protein used as a marker for an inhibitory interneuron subtype. Part of the ValidAbâ„¢ range of highly validated, data-rich antibodies.

    Host: Rabbit
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    Figure 1. Calretinin and Parvalbumin expressing interneurons in the rat hippocampus
    Pack:
    25μL
    Price:
    $171
    Qty:
    Pack:
    100μL
    Price:
    $382
    Qty:
    Supporting Docs Add to Favorites

  4. Anti-GAT1 Antibody ValidAbâ„¢ (HB7632)

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    Description:

    Antibody to GAT1 - GABA reuptake transporter and marker for GABAergic interneurones. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Rabbit
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    GAT1 expression in the rat cerebellum revealed with HB7632
    Pack:
    25μL
    Price:
    $179
    Qty:
    Pack:
    100μL
    Price:
    $536
    Qty:
    Supporting Docs Add to Favorites

  5. Anti-GFAP antibody ValidAbTM (HB8267)

    Description:

    Antibody to GFAP - cytoskeletal protein used as an astrocyte marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat
    Figure 1. GFAP expression in a rat cultured neurone preparation visualised using HB8267.
    Pack:
    25μg
    Price:
    $144
    Qty:
    Pack:
    100μg
    Price:
    $325
    Qty:
    Supporting Docs Add to Favorites

  6. Anti-GFAP antibody ValidAbTM (HB6406)

    Description:

    Antibody to GFAP - cytoskeletal protein used as an astrocyte marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Chicken
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    Figure 1. An astrocyte surrounded by neurons in a cultured rat neuron preparation.
    Pack:
    25μL
    Price:
    $164
    Qty:
    Pack:
    100μL
    Price:
    $366
    Qty:
    Supporting Docs Add to Favorites

  7. Anti-GFAP antibody ValidAbTM (HB8001)

    Description:

    Antibody to GFAP - cytoskeletal protein used as an astrocyte marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Rabbit
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    Anti-GFAP antibody ValidAb<sup>TM</sup>
    Pack:
    100μL
    Price:
    $371
    Qty:
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  8. Goat Anti-Mouse IgG H&L (AF488) preadsorbed ValidAbâ„¢ (HB8529)

    Description:

    Goat Anti-Mouse IgG H&L AF488 secondary antibody. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Goat
    Clonality: Polyclonal
    Goat Anti-Mouse IgG H&L (AF488) preadsorbed ValidAb™
    Pack:
    500μg
    Price:
    $130
    Qty:
    Pack:
    1mg
    Price:
    $194
    Qty:
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  9. Goat Anti-Mouse IgG H&L (Biotin) preadsorbed ValidAbTM (HB11345)

    Description:

    Goat Anti-Mouse IgG H&L (Biotin) preadsorbed secondary antibody. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Goat
    Clonality: Polyclonal
    Figure 1. Parvalbumin and Calretinin expressing interneurons in the rat hippocampus.
    Pack:
    500μg
    Price:
    $113
    Qty:
    Pack:
    1mg
    Price:
    $185
    Qty:
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Biological action
  1. Buffer
Applications
  1. Antineoplastic Agent
  2. Cell Culture
  3. ELISA
  4. FACS and flow cytometry
  5. fluorescence imaging
  6. ICC
  7. IF
  8. IHC
  9. IHC-P
  10. live cell imaging
  11. Plant Culture
  12. Selection Agent
  13. WB
  14. IHC(IF)
  15. Histoblot
  16. SDS-PAGE
Host
  1. Mouse
  2. Rabbit
  3. Goat
  4. Chicken
Clonality
  1. Monoclonal
  2. Polyclonal
Conjugate
  1. Janelia Fluor® 525
  2. Janelia Fluor® 549
  3. Janelia Fluor® 646
  4. AF488
  5. Biotin
Target
  1. GluN1
  2. GFAP
  3. NeuN
  4. Neurofilament L
  5. Beta III tubulin
  6. HSP60
  7. Neurofilament M
  8. MAP2
  9. Tyrosine hydroxylase
  10. Myelin basic protein
  11. GAT1
  12. c-Fos
  13. Vimentin
  14. BrdU
  15. Mouse IgG H&L
  16. Rabbit IgG H&L
  17. VGAT
  18. Parvalbumin
  19. Calretinin
  20. Calbindin
  21. Histone H3
  22. IBA1
  23. Chicken IgY H&L
  24. GluA1-4
  25. α-Synuclein