PI3K/Akt/mTOR

Serine protease inhibitor. Inhibits TMPRSS2 and partially blocks SARS-Cov2 entry in vitro.

ACE and LTA₄ hydrolase inhibitor

Rho/SRF pathway inhibitor. Induces intermediate mesoderm differentiation from ESCs.

Potent JAK inhibitor

Smo and hedgehog (Hh) signaling inhibitor. Also depletes stem like cancer cells and induces hESCs into endocrine cells.

Potent calcineurin inhibitor. Inhibits MPTP opening.

Na⁺ / K⁺ ATPase α subunit inhibitor. Antiviral.

Reversibly stimulates SERCA Ca²⁺-ATPase. V-ATPase inhibitor.

Selective ALK2 inhibitor. Promotes iPSC neurogenesis.

Potent, selective AMPK inhibitor. Promotes neural hPSCs differentiation and promotes cardiomyocyte differentiation in mESCs.