DREADDs

Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

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  1. Description:

    Novel DREADD agonist with high affinity and potency for hM3Dq and hM4Di. Active in vivo. Water soluble.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $102
    Qty:
    Pack:
    10mg
    Price:
    $199
    Qty:
    Pack:
    25mg
    Price:
    $420
    Qty:
    Pack:
    100mg
    Price:
    $1,548
    Qty:
  2. Description:

    Novel DREADD agonist with high affinity and potency for hM3Dq and hM4Di. Active in vivo. Freebase.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $94
    Qty:
    Pack:
    10mg
    Price:
    $165
    Qty:
    Pack:
    25mg
    Price:
    $363
    Qty:
    Pack:
    50mg
    Price:
    $605
    Qty:
    Pack:
    100mg
    Price:
    $1,095
    Qty:
  3. 5  Reviews
    Top Reviews:
    100% of 100
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    Description:

    Novel DREADD agonist with high affinity and potency for hM3Dq and hM4Di. Active in vivo. Water soluble.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $112
    Qty:
    Pack:
    10mg
    Price:
    $219
    Qty:
    Pack:
    25mg
    Price:
    $462
    Qty:
    Pack:
    50mg
    Price:
    $908
    Qty:
    Pack:
    100mg
    Price:
    $1,634
    Qty:
    Pack:
    50mM (add 1ml water)
    Price:
    $537
    Qty:
    Pack:
    100mM (add 1ml water)
    Price:
    $1,090
    Qty:
  4. MOMBA (HB7626)

    Description:

    Newly identified, highly selective FFA2-DREADD agonist

    Purity:

    >98%

    Pack:
    250mg
    Price:
    $50
    Qty:
  5. Olanzapine (HB1786)

    Description:

    5-HT2A and D2 antagonist. Potent DREADD agonist. Atypical antipsychotic.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $54
    Qty:
    Pack:
    50mg
    Price:
    $215
    Qty:
  6. Perlapine (HB4889)

    1  Review
    Top Reviews:
    100% of 100
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    Description:

    Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $33
    Qty:
    Pack:
    10mg
    Price:
    $132
    Qty:
    Pack:
    50mg
    Price:
    $545
    Qty:
  7. Description:

    Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator. Water soluble.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $44
    Qty:
    Pack:
    10mg
    Price:
    $133
    Qty:
    Pack:
    50mg
    Price:
    $558
    Qty:
  8. Pack:
    1mg
    Price:
    $73
    Qty:
    Pack:
    5mg
    Price:
    $149
    Qty:
    Pack:
    25mg
    Price:
    $517
    Qty:
  9. Description:

    Histamine H1 antagonist. Potent actuator of a modified hM4Di "GRANPA" DREADD receptor.

    Purity:

    >99%

    Pack:
    500mg
    Price:
    $54
    Qty:
    Pack:
    1g
    Price:
    $75
    Qty:
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