Antagonists & inhibitors
An antagonist is a drug or chemical that reduces the effect of an agonist. Competitive antagonists bind to the same site on a receptor as the agonist but do not activate it - thereby blocking the action of the agonist. Non-competitive antagonists block the action of the agonist by binding to a different site on the receptor (an allosteric or non-agonist site). A reversible antagonist binds non-covalently and can be washed out. An irreversible antagonist binds covalently and cannot be displaced by either competing ligands or washing. Inhibitors are drugs that can bind to a protein, such as an enzyme and decrease its activity. Researchers can save up to 50% on competitive antagonists, non-competitive antagonists, reversible and irreversible antagonists, and inhibitors from Hello Bio - they are up to half the price of other suppliers.
Bicifadine hydrochloride (HB1787)
Description:Potent noradrenalin transporter antagonist. Also 5-HT and dopamine transporter antagonist.
Purity:>98%
(+)-Bicuculline (HB0896)
Description:Prototypic, competitive GABAA receptor antagonist
Purity:>98%
(-)-Bicuculline methiodide (HB0893)
Description:Prototypic, competitive GABAA receptor antagonist
Purity:>98%
(-)-Bicuculline methobromide (HB0894)
Description:Prototypic, competitive GABAA receptor antagonist
Purity:>98%
(-)-Bicuculline methochloride (HB0895)
Description:Prototypic, competitive GABAA receptor antagonist
Purity:>98%
BIO (HB1259)
Description:Potent GSK-3α/β inhibitor. Maintains ESC self-renewal and pluripotency.
Purity:>98%