Antagonists & inhibitors
An antagonist is a drug or chemical that reduces the effect of an agonist. Competitive antagonists bind to the same site on a receptor as the agonist but do not activate it - thereby blocking the action of the agonist. Non-competitive antagonists block the action of the agonist by binding to a different site on the receptor (an allosteric or non-agonist site). A reversible antagonist binds non-covalently and can be washed out. An irreversible antagonist binds covalently and cannot be displaced by either competing ligands or washing. Inhibitors are drugs that can bind to a protein, such as an enzyme and decrease its activity. Researchers can save up to 50% on competitive antagonists, non-competitive antagonists, reversible and irreversible antagonists, and inhibitors from Hello Bio - they are up to half the price of other suppliers.
Pyripyropene A (HB4044)
Description:Highly specific acyl-coenzyme A cholesterol acetyltransferase 2 inhibitor
Purity:>95%
QNZ 46 (HB0541)
Description:GluN2C/D selective, non-competitive NMDA receptor antagonist
Purity:>98%
Quetiapine hemifumarate (HB1803)
Description:5-HT2 and D2 antagonist. Atypical antipsychotic.
Purity:>99%
Q-VD-OPh (HB4048)
Description:Cell permeable, irreversible and non-toxic pan-caspase inhibitor
Purity:>95%