Antagonists & inhibitors
An antagonist is a drug or chemical that reduces the effect of an agonist. Competitive antagonists bind to the same site on a receptor as the agonist but do not activate it - thereby blocking the action of the agonist. Non-competitive antagonists block the action of the agonist by binding to a different site on the receptor (an allosteric or non-agonist site). A reversible antagonist binds non-covalently and can be washed out. An irreversible antagonist binds covalently and cannot be displaced by either competing ligands or washing. Inhibitors are drugs that can bind to a protein, such as an enzyme and decrease its activity. Researchers can save up to 50% on competitive antagonists, non-competitive antagonists, reversible and irreversible antagonists, and inhibitors from Hello Bio - they are up to half the price of other suppliers.
(R)-3-Hydroxybutyric acid (HB4640)
Description:Endogenous HDAC1, HDAC3 and HDAC4 inhibitor
Purity:>98%
(S)-3-Hydroxybutyric acid (HB4641)
Description:Endogenous HDAC1, HDAC3 and HDAC4 inhibitor
Purity:>98%
- Description:
Synthetic estrogen receptor ligand. Widely used in genome engineering (e.g. CreER/ CRISPR-Cas9).
Purity:>98%
- Description:
Estrogen receptor ligand. For inducible genome manipulation (e.g. Cre-LoxP (CreER)/ TRAP/ CRISPR-Cas9).
Purity:>98%
(R,R)-Hymeglusin (HB3701)
Description:Specific and irreversible HMG-CoA synthase inhibitor
Purity:>95%
10Z-Hymenialdisine (HB1264)
Description:Pan kinase inhibitor. Potently inhibits MEK1, Cdk1, Cdk2, Cdk3 and Cdk5 and GSK-3β.
Purity:>97%
I-BET 151 hydrochloride (HB1446)
Description:BET bromodomain inhibitor, also promotes differentiation of hiPSCs into megakaryocytes
Purity:>98%