Antagonists & inhibitors
An antagonist is a drug or chemical that reduces the effect of an agonist. Competitive antagonists bind to the same site on a receptor as the agonist but do not activate it - thereby blocking the action of the agonist. Non-competitive antagonists block the action of the agonist by binding to a different site on the receptor (an allosteric or non-agonist site). A reversible antagonist binds non-covalently and can be washed out. An irreversible antagonist binds covalently and cannot be displaced by either competing ligands or washing. Inhibitors are drugs that can bind to a protein, such as an enzyme and decrease its activity. Researchers can save up to 50% on competitive antagonists, non-competitive antagonists, reversible and irreversible antagonists, and inhibitors from Hello Bio - they are up to half the price of other suppliers.
D-AP5 (HB0225)
Description:Selective, competitive NMDA receptor antagonist. Inhibits NMDAR-synaptic plasticity.
Purity:>99%
L-Ascorbic acid (HB1238)
Description:Antioxidant. Enhances iPSC generation and increases reprogramming efficiency. Supports mesenchymal stem cell proliferation.
Purity:>99%
Bafilomycin A1 (HB1125)
Description:Highly potent, selective V-ATPase inhibitor. Autophagy inhibitor.
Purity:>98%
Brefeldin A (BFA) (HB2949)
Description:Reversible protein transport inhibitor. Commonly used in cytokine staining. Enhances CRISPR-mediated HDR.
Purity:>98%
- Description:
Fluorescent β2 adrenoceptor antagonist
Caffeine (HB2846)
Description:Non-selective, competitive adenosine receptor antagonist / PDE inhibitor
Calphostin C (HB0160)
Description:Potent, selective PKC inhibitor. Also antagonizes the Tcf/β-catenin complex
Purity:>95%
Calyculin A (HB0161)
Description:Potent, selective protein phosphatase 1 / 2A inhibitor
Purity:>98%
(S)-4-Carboxyphenylglycine (HB0049)
Description:Competitive, selective group 1 mGlu antagonist
Purity:>99%