Antagonists & inhibitors
An antagonist is a drug or chemical that reduces the effect of an agonist. Competitive antagonists bind to the same site on a receptor as the agonist but do not activate it - thereby blocking the action of the agonist. Non-competitive antagonists block the action of the agonist by binding to a different site on the receptor (an allosteric or non-agonist site). A reversible antagonist binds non-covalently and can be washed out. An irreversible antagonist binds covalently and cannot be displaced by either competing ligands or washing. Inhibitors are drugs that can bind to a protein, such as an enzyme and decrease its activity. Researchers can save up to 50% on competitive antagonists, non-competitive antagonists, reversible and irreversible antagonists, and inhibitors from Hello Bio - they are up to half the price of other suppliers.
Pluripotin (HB2223)
Description:Dual ERK1/RasGAP inhibitor. Maintains ESC self-renewal.
Purity:>98%
PluriSln 1 (HB3573)
Description:SCD1 inhibitor. Selectively eliminates undifferentiated hPSCs from culture.
Purity:>99%
PLX4720 (HB4030)
Description:Potent and selective cell permeable B-Raf and C-Raf inhibitor
Purity:>99%
PNU 37883 hydrochloride (HB1105)
Description:Selective vascular KATP channel antagonist
Purity:>99%