Antagonists & inhibitors
An antagonist is a drug or chemical that reduces the effect of an agonist. Competitive antagonists bind to the same site on a receptor as the agonist but do not activate it - thereby blocking the action of the agonist. Non-competitive antagonists block the action of the agonist by binding to a different site on the receptor (an allosteric or non-agonist site). A reversible antagonist binds non-covalently and can be washed out. An irreversible antagonist binds covalently and cannot be displaced by either competing ligands or washing. Inhibitors are drugs that can bind to a protein, such as an enzyme and decrease its activity. Researchers can save up to 50% on competitive antagonists, non-competitive antagonists, reversible and irreversible antagonists, and inhibitors from Hello Bio - they are up to half the price of other suppliers.
Tetrodotoxin (citrate free) (HB1034)
Description:Potent, selective, use-dependent Na+ channel blocker. Citrate free.
Purity:>99%
Tetrodotoxin citrate (HB1035)
Description:Potent, selective, use-dependent Na+ channel blocker. Citrate Salt.
Purity:>99%
Zatebradine hydrochloride (HB1151)
Description:HCN channel blocker. Potent, selective bradycardic agent.
Purity:>95%
ZD 7288 (HB1152)
Description:HCN channel blocker. Modulates sino-atrial node function.
Purity:>98%