Antagonists & inhibitors
An antagonist is a drug or chemical that reduces the effect of an agonist. Competitive antagonists bind to the same site on a receptor as the agonist but do not activate it - thereby blocking the action of the agonist. Non-competitive antagonists block the action of the agonist by binding to a different site on the receptor (an allosteric or non-agonist site). A reversible antagonist binds non-covalently and can be washed out. An irreversible antagonist binds covalently and cannot be displaced by either competing ligands or washing. Inhibitors are drugs that can bind to a protein, such as an enzyme and decrease its activity. Researchers can save up to 50% on competitive antagonists, non-competitive antagonists, reversible and irreversible antagonists, and inhibitors from Hello Bio - they are up to half the price of other suppliers.
Ro 32-0432 hydrochloride (HB4820)
Description:Potent, selective PKC inhibitor. GRK inhibitor.
Purity:>98%
Ro 61-8048 (HB0556)
Description:Potent, competitive kynurenine 3-hydroxylase inhibitor
Purity:>99%
(R)-(-)-Rolipram (HB2898)
Description:Potent, selective PDE4 inhibitor. Enantiomer of Rolipram.
Purity:>98%