Glutamate uptake & transport
Glutamate transport is mediated by a family of transmembrane proteins known as glutamate transporters, or excitatory amino acid transporters (EAATs). EAATs are sodium- and potassium-dependent members of the Solute Carrier Family 1 (SLC1). The five EAAT subtypes are EAAT1 (Excitatory amino acid transporter 1 / SLC1A3) , EAAT2 (Excitatory amino acid transporter 2 / SLC1A2), EAAT3 (Excitatory amino acid transporter 3 / SLC1A1), EAAT4 (Excitatory amino acid transporter 4 / SLC1A6) and EAAT5 (Excitatory amino acid transporter 5 / SLC1A7). Researchers can save up to 50% on EAAT inhibitors, activators and modulators from Hello Bio - they are up to half the price of other suppliers.
A83-01 (HB3218)
Description:Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.
Purity:>98%
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AM 404 (HB1174)
Description:Selective, competitive carrier-mediated anandamide transport inhibitor
Purity:>98%
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Amitriptyline hydrochloride (HB1794)
Description:Serotonin/norepinephrine reuptake inhibitor (SNRI)
Purity:>98%
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Brefeldin A (BFA) (HB2949)
Description:Reversible protein transport inhibitor. Commonly used in cytokine staining. Enhances CRISPR-mediated HDR.
Purity:>98%
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Calphostin C (HB0160)
Description:Potent, selective PKC inhibitor. Also antagonizes the Tcf/β-catenin complex
Purity:>95%
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Calyculin A (HB0161)
Description:Potent, selective protein phosphatase 1 / 2A inhibitor
Purity:>98%
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CHIR 99021 (HB1261)
Description:Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons.
Purity:>98%
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