Transporters
Transporters are integral transmembrane proteins involved in the movement of ions, small molecules, peptides, lipids or macromolecules, such as another protein, across a biological membrane. The energy required for active transport processes is obtained by hyrdolyzing ATP or by utilising ion gradients. The three major classes of ATP-driven transporters are: P-type ATPases (eg. Ca2+-ATPases and Na+,K+-ATPases); F-type or V-type ATPases and ATP-binding cassette transporters. The solute carrier family of transporters include the biogenic amine transporters (NET, DAT and SERT) the Na+/H+ exchanger, glutamate transporters (EAAT) and GABA transporters (GAT). Researchers can save up to 50% on transporter blockers and inhibitors from Hello Bio – they are up to half the price of other suppliers and have been reviewed and cited by researchers worldwide.
View transporter products: Cannabinoid | Dopamine | GABA | Glutamate | Glycine | Monoamine | Multidrug Transporter | Na+ / Ca2+ exchangers | Na+ / H+ exchangers | Norepinephrine | Serotonin (5-HT)
RG 108 (HB1377)
Description:Non-nucleoside DNA methyltransferase inhibitor. Enhances iPSC generation efficiency.
Purity:>99%
-
SB 202190 (HB1301)
Description:Potent ATP competitive p38 MAPK inhibitor. 3D growth matrix component, promotes long-term organoid growth and can be used in production of gastric organoids. Promotes stability of human pluripotent stem cells.
Purity:>99%
-
SB 203580 (HB1302)
Description:Potent, selective p38 MAPK inhibitor. Stimulates neural stem cell proliferation.
Purity:>98%
-
SB 216763 (HB1272)
Description:Potent, selective cell permeable GSK-3 inhibitor. Maintains mESCs and promotes retinal stem cells proliferation.
Purity:>98%
-
SB 431542 (HB3555)
Description:Potent, selective TGF-βRI ALK5, ALK4, ALK7 inhibitor. Induces sheet formation, proliferation, differentiation of ESC-derived endothelial cells and replaces SOX2 in reprogramming protocols.3D growth matrix component and can be used in production of organoids.
Purity:>98%
-
Sodium butyrate (HB1399)
Description:HDAC inhibitor. Directs mESC differentiation into hepatocytes.
-
SP600125 (HB2234)
Description:Selective, ATP-competitive JNK inhibitor. Prevents BMP9-induced osteogenic MSC differentiation. Maintains stem cells in naive pluripotent state.
Purity:>98%
-
-
Stauprimide (HB3011)
Description:NME2 nuclear translocation inhibitor. Primes ESCs for differentiation.
Purity:>98%
-
SU 5402 (HB3133)
Description:Potent FGFR and VEGFR inhibitor. Attenuates integrin β4-induced neural stem cell differentiation.
Purity:>95%
