Nuclear Receptors
Nuclear hormone receptors (nuclear receptors) are specialised transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can save up to 50% on nuclear hormone receptor agonists, antagonists and modulators from Hello Bio - they are up to half the price of other suppliers.
-
(S)-MCPG sodium salt (HB6112)
Description:Non-selective group I and II mGluR antagonist. Water soluble sodium salt.
Purity:>99%
-
(R,S)-MCPG sodium salt (HB0038)
Description:Water soluble, non-selective group I and II mGluR antagonist
Purity:>98%
-
-
-
Mianserin hydrochloride (HB1658)
Description:Non-selective 5-HT2 receptor antagonist. Shows activity at other receptors.
Purity:>99%
-
Mifepristone (HB2783)
Description:Potent glucocorticoid and progesterone receptor antagonist. Also used for gene editing as a mifepristone inducible Cas9 and Cpf1 CRISPR effector.
Purity:>99%
-
(-)-MK 801 maleate (HB0003)
Description:NMDA receptor antagonist. Less active enantiomer of (+)-MK 801.
Purity:>99%
-
(+)-MK 801 maleate (HB0004)
Description:Potent, selective, non-competitive NMDA receptor antagonist
Purity:>98%
