Nuclear Receptors
Nuclear hormone receptors (nuclear receptors) are specialised transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can save up to 50% on nuclear hormone receptor agonists, antagonists and modulators from Hello Bio - they are up to half the price of other suppliers.
WAY 100635 maleate (HB1790)
Description:Potent 5-HT1A receptor antagonist. D4 receptor agonist.
Purity:>99%
YM 298198 hydrochloride (HB0664)
Description:Potent, selective, non-competitive mGlu1 antagonist
Purity:>99%
Zacopride hydrochloride (HB1694)
Description:Potent 5-HT3 antagonist and 5-HT4 agonist. Also selective IK1 channel agonist.
Purity:>99%
Ziprasidone hydrochloride (HB1753)
Description:5-HT2A and D2 antagonist. Atypical antipsychotic.
Purity:>99%
Zotepine (HB1778)
Description:5-HT2A and dopamine D2 receptor antagonist. Atypical antipsychotic.
Purity:>99%