Group I (mGlu5, mGlu1)
Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.
SR 95531 hydrobromide (Gabazine) (HB0901)
Description:Selective, competitive GABAA receptor antagonist
Purity:>98%
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(S)-(-)-Sulpiride (HB1836)
Description:Selective D2-like receptor antagonist. Active enantiomer.
Purity:>99%
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(RS)-(±)-Sulpiride (HB1835)
Description:Standard D2-like dopamine receptor antagonist
Purity:>98%
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Talampanel (HB0600)
Description:Selective, non-competitive AMPA / kainate receptor antagonist
Purity:>98%
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Tamoxifen (HB0601)
Description:Estrogen receptor antagonist/ partial agonist. May be used in genome engineering (e.g. CreER/ CRISPR-Cas9).
Purity:>99%
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Tamoxifen Citrate (HB0602)
Description:Estrogen receptor antagonist/ partial agonist. May be used in genome engineering (e.g. CreER/ CRISPR-Cas9). Citrate salt.
Purity:>98%
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TCN 201 (HB0604)
Description:Potent, non-competitive GluN2A subunit selective NMDA receptor antagonist
Purity:>99%
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