Group I (mGlu5, mGlu1)
Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.
SB 269970 hydrochloride (HB1684)
Description:Potent, selective 5-HT7 receptor antagonist
Purity:>98%
SCH 23390 hydrochloride (HB1643)
Description:Potent, selective D1-like receptor antagonist
Purity:>98%
SKF 83566 hydrobromide (HB1863)
Description:Potent, selective D1-like receptor antagonist
Purity:>98%
Spiperone hydrochloride (HB1656)
Description:Selective D2-like receptor antagonist. 5-HT2A antagonist.
Purity:>98%
Spironolactone (HB2799)
Description:Mineralocorticoid and androgen receptor antagonist
Purity:>98%