DREADD

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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

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  1. 27  Reviews
    Top Reviews:
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    Description:

    Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator. Brain penetrant. Water soluble.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $33
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    Pack:
    5mg
    Price:
    $88
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    Pack:
    10mg
    Price:
    $157
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    Pack:
    25mg
    Price:
    $361
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    Pack:
    50mg
    Price:
    $583
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    Pack:
    100mg
    Price:
    $1,045
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  2. Description:

    Potent CK2 inhibitor

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $58
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  3. Endomorphin-1 (HB2410)

    Description:

    Potent, selective μ-opioid receptor agonist

    Pack:
    5mg
    Price:
    $94
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  4. Endomorphin-2 (HB2411)

    Description:

    Potent, selective μ-opioid receptor agonist

    Purity:

    >95%

    Pack:
    5mg
    Price:
    $90
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  5. Pack:
    1g
    Price:
    $48
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    Pack:
    5g
    Price:
    $103
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  6. Pack:
    10mg
    Price:
    $119
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    Pack:
    50mg
    Price:
    $519
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  7. Description:

    D2 receptor antagonist

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $156
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    Pack:
    50mg
    Price:
    $587
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    Pack:
    25mg
    Price:
    $257
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  8. Pack:
    10mg
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    Pack:
    50mg
    Price:
    $382
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  9. Pack:
    50mg
    Price:
    $227
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    Pack:
    10mg
    Price:
    $53
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