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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
MK-2206 dihydrochloride (HB5934)
Description:Highly selective, pan-Akt inhibitor. Autophagy and apoptosis inducer. Orally bioavailable.
Purity:>98%
Okadaic Acid Sodium Salt (HB0470)
Description:Water soluble, potent protein phosphatase 1 and 2A inhibitor
Purity:>98%