DREADD
Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
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ISX 9 (HB3401)
Description:Neurogenic agent. Induces SVZ progenitor neuronal differentiation and cardiomyogenic differentiation.
Purity:>99%
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KC159 (HB7601)
Description:Novel, selective Piezo1 channel activator. Improved efficacy and potency compared to Yoda1.
Purity:>98%
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ML 336 (K2P2.1/ TREK-1 modulator) (HB7386)
Description:Covalent K2P2.1 (TREK-1) modulator
Purity:>99%
