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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
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Nociceptin (HB2424)
Description:Endogenous NOP agonist. Involved in a variety of physiological processes.
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±-Octopamine hydrochloride (HB2791)
Description:Invertebrate neurotransmitter. Chemogenetic DmOctβ1 receptor activator.
Purity:>99%
- Description:
Growth factor implicated in various nervous system functions.
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Recombinant mouse MANF protein (HB6565)
Description:Neurotrophic factor with neuroprotective effects
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