DREADD
Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
Kynurenic acid (HB0362)
Description:Endogenous ionotropic glutamate / nicotinic antagonist.
Purity:>98%
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LY-367385 hydrochloride (HB5153)
Description:Potent, highly selective mGlu1a antagonist. Water soluble.
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- Description:
Novel caged, fast-equilibrating glutamate receptor antagonist. Suitable for use as a synaptic probe.
Purity:>98%
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MRS 2179 ammonium salt (HB4241)
Description:Selective P2Y1 antagonist. Inhibits platelet aggregation.
Purity:>98%
