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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
Ifenprodil (HB0339)
Description:Non-competitive GluN2B subunit selective NMDAR allosteric inhibitor
Purity:>99%
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JNJ 10191584 maleate (HB1596)
Description:Potent, selective H4 receptor silent antagonist
Purity:>99%
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Kynurenic acid (HB0362)
Description:Endogenous ionotropic glutamate / nicotinic antagonist.
Purity:>98%
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Kynurenic acid sodium salt (HB0363)
Description:Endogenous ionotropic glutamate / nicotinic antagonist. Sodium salt.
Purity:>98%
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