DREADD
Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
JC-1 (HB0791)
Description:Mitochondrial membrane potential indicator/dye. Widely used in apoptosis studies.
Purity:>95%
Janelia Fluor® 549, free acid (HB8745)
Description:Yellow dye supplied as a free acid. Suitable for dSTORM, STED, confocal microscopy, live cell imaging and flow cytometry.
Janelia Fluor® 549, SE (HB7336)
Description:Yellow dye for coupling to NHS groups. Suitable for dSTORM, STED, confocal microscopy, live cell imaging and flow cytometry.
Methylene Blue (HB0409)
Description:Biological dye, redox indicator and soluble guanylyl cyclase inhibitor
Oxazole Yellow Iodide (HB6210)
Description:Oxazole Yellow iodide is also known as Yo-Pro-1. It is a commonly used apoptosis marker.