DREADD
Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
Fura-2 AM (Cell permeant) (HB0780)
Description:High affinity, cell permeable calcium indicator which is ratiometric and UV light excitable
FURA-2 (HB0779)
Description:Widely used UV light-excitable, ratiometric calcium indicator
Purity:>90%
Hoechst 33342 (HB0787)
Description:Blue fluorescent DNA stain. Cell permeable. Nuclear stain.
Purity:>98%
- Description:
Blue fluorescent DNA stain. Nuclear stain. 10mg/ml staining solution in water. Solid also available in 50mg and 100mg.
Janelia Fluor® 525, free acid (HB7173)
Description:Yellow dye supplied as a free acid. Suitable for super resolution microscopy (e.g. dSTORM), confocal microscopy and live cell imaging.
Janelia Fluor® 525, SE (HB8455)
Description:Yellow dye for coupling to NHS groups. Suitable for super resolution microscopy (e.g. dSTORM), confocal microscopy and live cell imaging.
Janelia Fluor® 549, Azide (HB7988)
Description:Yellow dye supplied as an azide for click chemistry. Suitable for dSTORM, STED, confocal microscopy, live cell imaging and flow cytometry.
Janelia Fluor® 549, Tetrazine (HB7228)
Description:Yellow dye supplied with a tetrazine reactive handle for copper-free click chemistry. Suitable for dSTORM, STED, confocal microscopy and live cell imaging.