DREADD
Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
- Description:
Antibody to tyrosine hydroxylase (TH) - the rate limiting enzyme in catecholamine synthesis and used as a marker for catecholaminergic (dopaminergic and noradrenergic) neurones in the CNS. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: ChickenClonality: PolyclonalReactivity Tested: Mouse, Rat - Description:
Antibody to tyrosine hydroxylase (TH) - the rate limiting enzyme in catecholamine synthesis and used as a marker for catecholaminergic (dopaminergic and noradrenergic) neurones in the CNS. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: Mouse, Rat - Description:
Antibody to VGAT - GABA transporter and GABAergic neuron marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: RabbitClonality: PolyclonalReactivity Tested: Mouse, Rat Anti-Vimentin antibody ValidAb™ (HB6497)
Description:Monoclonal antibody to Vimentin - class III intermediate filament expressed in mesenchymal cells used as a marker of epithelial-mesenchymal transition. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: Rat, Human, Mouse (no staining)Anti-BrdU antibody ValidAbTM (HB9919)
Description:Antibody to BrdU - thymidine analogue incorporated into DNA during replication therefore used as a marker of proliferating cells. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: NAAnti-Calbindin antibody ValidAb™ (HB6396)
Description:Antibody to Calbindin - calcium binding protein used as a marker for an inhibitory interneuron subtype. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: RatAnti-GluN1 antibody ValidAbTM (HB7535)
Description:Antibody to the GluN1 subunit of the NMDA receptor. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: Mouse, Rat- Description:
Goat Anti-Mouse IgG H&L Janelia Fluor® 549 secondary antibody. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: GoatClonality: Polyclonal - Description:
Goat Anti-Mouse IgG H&L Janelia Fluor® 525 secondary antibody. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: GoatClonality: Polyclonal - Description:
Antifade fluorescence hard-set mounting medium for use in IHC(IF) and ICC.