G protein coupled receptors
G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
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Zebularine (HB1378)
Description:DNA methyltransferase inhibitor. Induces cardiomyocyte differentiation in MSCs.
Purity:>99%
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Z-Leu-Leu-Leu-B(OH)2 (MG-262) (HB4134)
Description:Highly potent, selective, cell permeable proteasome inhibitor. More potent than MG-132.
Purity:>95%
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ZM 447439 (HB1444)
Description:Potent, selective, ATP-competitive Aurora kinase B inhibitor
Purity:>99%
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Zoniporide dihydrochloride (HB1137)
Description:Potent, selective Na+ / H+ exchanger-1 inhibitor
Purity:>99%
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Z-VAD-(OMe)-FMK (HB1319)
Description:Irreversible, cell permeable, broad spectrum caspase inhibitor.
Purity:>95%
