G protein coupled receptors

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G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.

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Items 61-70 of 312

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  1. Cyclopamine (HB2965)

    Description:

    Smo and hedgehog (Hh) signaling inhibitor. Also depletes stem like cancer cells and induces hESCs into endocrine cells.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $196
    Qty:
    Pack:
    5mg
    Price:
    $746
    Qty:
  2. Description:

    Potent SERCA1a inhibitor

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $95
    Qty:
    Pack:
    50mg
    Price:
    $451
    Qty:
  3. Cyclosporin A (HB0220)

    Description:

    Potent calcineurin inhibitor. Inhibits MPTP opening.

    Purity:

    >99%

    Pack:
    100mg
    Price:
    $96
    Qty:
  4. Pack:
    10mg
    Price:
    $213
    Qty:
    Pack:
    50mg
    Price:
    $827
    Qty:
  5. Pack:
    100mg
    Price:
    $147
    Qty:
    Pack:
    500mg
    Price:
    $591
    Qty:
  6. Pack:
    5mg
    Price:
    $78
    Qty:
    Pack:
    25mg
    Price:
    $311
    Qty:
    Pack:
    10mg
    Price:
    $74
    Qty:
  7. Description:

    Selective serotonin reuptake inhibitor (SSRI)

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $116
    Qty:
    Pack:
    50mg
    Price:
    $414
    Qty:
  8. DAPT (HB3345)

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    Description:

    γ-secretase inhibitor and classical notch inhibitor. Induces neuronal differentiation. 3D Growth matrix component and used in cerebral organoid differentiation media.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    Qty:
    Pack:
    10mg
    Price:
    $168
    Qty:
    Pack:
    25mg
    Price:
    $418
    Qty:
    Pack:
    50mg
    Price:
    $703
    Qty:
    Pack:
    10mM (1mL in DMSO)
    Price:
    $109
    Qty:
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