G protein coupled receptors
G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
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A 769662 (HB1351)
Description:Potent, reversible AMPK activator. Inhibits MSC proliferation.
Purity:>98%
L-Ascorbic acid (HB1238)
Description:Antioxidant. Enhances iPSC generation and increases reprogramming efficiency. Supports mesenchymal stem cell proliferation.
Purity:>99%
Recombinant human BDNF protein (HB3485)
Description:Member of the neurotrophin growth factor family. Plays an important role in synaptic plasticity and neurogenesis.
8-Bromo-cAMP sodium salt (8-Br-cAMP) (HB0090)
Description:Cell permeable PKA activator
Purity:>99%
- Description:
Dihydrochloride salt of CNO - the prototypical DREADD activator
Purity:>98%
Forskolin (HB1348)
Description:Cell permeable, reversible adenylyl cyclase activator. Neuronal differentiation inducer. Used in production of liver organoids.
Purity:>98%
(Z)-4-Hydroxytamoxifen (Z-4-OHT) (HB2508)
Description:Synthetic estrogen receptor ligand. Widely used in genome engineering (e.g. CreER/ CRISPR-Cas9).
Purity:>98%
- Description:
Synthetic estrogen receptor ligand. Widely used in genome engineering (e.g. CreER/ CRISPR-Cas9).
Purity:>98%
- Description:
Estrogen receptor ligand. For inducible genome manipulation (e.g. Cre-LoxP (CreER)/ TRAP/ CRISPR-Cas9).
Purity:>98%